Skip to main content
SpringerPlus
Figure 1 | SpringerPlus

Figure 1

From: CyberKnife multisession stereotactic radiosurgery and hypofractionated stereotactic radiotherapy for perioptic meningiomas: intermediate-term results and radiobiological considerations

Figure 1

Graph showing total doses of radiation associated with a predicted biologically equivalent effect on meningioma control for various numbers of equal daily fractions (turquoise line). Calculations were based on the linear quadratic model considering isoeffective 13–14 Gy delivered in single fraction and 54 Gy in 30 fractions. Each dose corresponds to a biologically equivalent dose BED of 102.6 Gy an α/β of 2. Low risk of optic neuropathy as a function of the number of equal daily fractions were also calculated to understand the range of dose to be delivered to the optic apparatus at a specific dose/fraction scheme. Calculations were based on the “optic ret” model of Goldsmith et al. (1992), with an equivalent optic ret dose of 890 (red line) and using the linear quadratic model and considering isoeffective 11 Gy delivered in single fraction and 50 Gy in 25 fractions (purple line).

Back to article page