Figure 2From: ATM gene mutations in sporadic breast cancer patients from Brazil Representative examples of the sequencing analysis of potential ATM mutations in sporadic breast cancer patients. A, upper panel: reference sequence; B, middle panel: sequencing electropherograms from normal tissue samples from breast cancer patients (227Â N, 231Â N, 214Â N, and 72NL); C, lower panel: sequencing electropherograms from tumor tissue samples from breast cancer patients (227Â T, 231Â T, 214Â T, and 72TL). Case 227 showed two potential ATM missense mutations without evidence of LOH; Cases 214 and 231 showed potential ATM mutations with evidence of loss of the wild type allele.Back to article page