Table 2 Frequency of CHEK2 1100delC mutation in breast cancer cases and controls by ethnicity
Overall | Overall | Carriers n (frequency of carriers, %) | Carriers n (frequency of carriers, %) | ||||
|---|---|---|---|---|---|---|---|
Study | Population | Year | Case | Control | Case | Control | Reference |
América | |||||||
1. Meijers-Heijboer and al | USA | 2002 | 264 | 166 | 6 (2.3) | 1(0.6) | (Meijers-Heijboer et al. 2002) |
2. Offit KPH and al | USA | 2003 | 67 | 569 | 0 (0) | 2 (0.4) | (Offit et al. 2003) |
3. Pereira and al | USA | 2004 | 829 | 859 | 9 (1.1) | 4(0.5) | (Mateus Pereira et al. 2004) |
4. Friedrichsen and al | USA | 2004 | 506 | 459 | 6 (1.2) | 2 (0.4) | (Friedrichsen et al. 2004) |
5. Bernstein and al | CANADA | 2006 | 1199 | 496 | 18 (1.34) | 1 (0.2) | (Bernstein et al. 2006) |
6. Novak and al | CANADA | 2008 | 149 | 141 | 3 (2.01) | 1 (0.7) | (Novak et al. 2008) |
7. Shiyu Zhang and al | CANADA | 2008 | 560 | 6460 | 4 (0.7) | 19 (0.3) | (Zhang et al. 2008) |
8. Gonzalez-Hormazabal and al | CHILE | 2008 | 196 | 1124 | 0 (0) | 0 (0) | (Gonzalez-Hormazabal et al. 2008) |
9. Shiyu Zhang and al | BRAZIL | 2008 | 155 | 377 | 1 (0.7) | 0 (0) | (Zhang et al. 2008) |
10. Bell DW | LATINAS | 2007 | 362 | 384 | 1 | 0 (0) | (Sodha et al. 2007) |
Europe | |||||||
Sodha and al | UNITED KINGDOM | 2002 | 68 | 300 | 3(4.4) | 0(0) | (Sodha et al. 2002) |
Check2 Consortium | UNITED KINGDOM | 2004 | 2886 | 3749 | 35(1.2) | 20 (0.53) | (CHEK2 Breast Cancer Case–control Consortium CHEK2*1100delC and susceptibility to breast cancer 2004) |
Meijers-Heijboer and al | UNITED KINGDOM | 2002 | 564 | 288 | 7(1.3) | 1(0.35) | (Meijers-Heijboer et al. 2002) |
Meijers-Heijboer and al | THE NETHERLANDS | 2002 | 79 | 460 | 2(2.5) | 6(1.2) | (Meijers-Heijboer et al. 2002) |
Oldenburg and al | THE NETHERLANDS | 2003 | 237 | 212 | 27(11.4) | 6(2.8) | (Oldenburg et al. 2003) |
Check2 Consortium | THE NETHERLANDS | 2004 | 1706 | 184 | 65(3.8) | 3(1.6) | (CHEK2 Breast Cancer Case–control Consortium CHEK2*1100delC and susceptibility to breast cancer 2004) |
De Jong and al | THE NETHERLANDS | 2005 | 962 | 367 | 28(2.9) | 5(1.4) | (De Jong et al. 2005) |
Offit KPH and al | ASHKENAZI JEWISH | 2003 | 33 | 1096 | 1(3) | 3(0.3) | (Offit et al. 2003) |
Shiyu Zhang and al | JEWISH | 2008a | 320 | 180 | 4(1.3) | 0(0) | (Zhang et al. 2008) |
McInerney and al | IRELAND | 2009 | 903 | 1016 | 5(0.5) | 1(0.1) | (McInerney et al. 2009) |
Martinez-Bouzas and al | BASQUE COUNTRY | 2007 | 214 | 120 | 2(0.93) | 0(0) | (Martınez-Bouzas et al. 2007) |
Cybulski and al | POLAND | 2004a | 1017 | 4000 | 5(0.5) | 10(0.25) | (Cybulski et al. 2004) |
Cybulski and al | POLAND | 2007b | 4454 | 5496 | 20(0.4) | 12(0.2) | (Cybulski et al. 2007) |
Kleibl and al | CZECH REPUBLIC | 2005 | 1046 | 730 | 4(0.38) | 2(0.27) | (Kleibl et al. 2005) |
Check2 Consortium | GERMANY | 2004 | 985 | 401 | 11(1.1) | 1(0.25) | (CHEK2 Breast Cancer Case–control Consortium CHEK2*1100delC and susceptibility to breast cancer 2004) |
Dufault and al | GERMANY | 2004 | 516 | 1315 | 8(1.6) | 6(0.5) | (Dufault et al. 2004) |
Rashid and al | GERMANY | 2005 | 613 | 651 | 5(0.82) | 6(0.92) | (Rashid et al. 2005) |
Einarsdottir and al | SWEDEN | 2006 | 1510 | 1334 | 20(0.7) | 8(0.4) | (Einarsdottir et al. 2006) |
Margollin and | SWEDEN | 2007 | 450 | 760 | 10(2.2) | 5(0.7) | (Margolin et al. 2007) |
Weischer and al | DENMARK | 2007 | 1088 | 4643 | 13(1.1) | 22(0.5) | (Weischer et al. 2007) |
Vahteristo and al | FINLAND | 2002 | 1035 | 1885 | 21(2.1) | 26 (1.4) | (Vahteristo et al. 2002) |
Check2 Consortium | FINLAND | 2004 | 464 | 447 | 13(2.9) | 5(1.1) | (CHEK2 Breast Cancer Case–control Consortium CHEK2*1100delC and susceptibility to breast cancer 2004) |
Kirsi and al | FINLAND | 2011 | 82 | 380 | 3(0.037) | 6(0.016) | (Kuusisto Kirsi et al. 2011) |
Osorio and al | SPAIN | 2004 | 456 | 400 | 0(0) | 0(0) | (Osorio et al. 2004) |
Caligo and al | ITALY | 2004 | 939 | 334 | 1(0.1) | 0(0) | (Caligo et al. 2004) |
Baeyens and al | BELGIUM | 2005 | 178 | 100 | 4(2.24) | 0(0) | (Baeyens et al. 2005) |
Asia | |||||||
Shiyu Zhang and al | FILIPINO | 2008 | 342 | 7 | 0(0) | 0(0) | (Zhang et al. 2008) |
Chekmariova and al | RUSSIA | 2006 | 815 | 448 | 22(5.2) | 1(0.2) | (Chekmariova et al. 2006) |
Bell DW | JAPANE | 2007 | 428 | 378 | 0(0) | 0(0) | (Sodha et al. 2007) |
Rajkumar T and al | SOUTH INDIA | 2003 | 22 | 1 | 0(0) | 0(0) | (Rajkumar et al. 2003) |
Africa | |||||||
Present study | MOROCCO | 2013 | 134 | 114 | 0(0) | 0(0) | Present study |