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Table 2 Frequency of CHEK2 1100delC mutation in breast cancer cases and controls by ethnicity

From: The CHEK2 1100delC allelic variant is not present in familial and sporadic breast cancer cases from Moroccan population

    Overall Overall Carriers n (frequency of carriers, %) Carriers n (frequency of carriers, %)  
Study Population Year Case Control Case Control Reference
América        
1. Meijers-Heijboer and al USA 2002 264 166 6 (2.3) 1(0.6) (Meijers-Heijboer et al. 2002)
2. Offit KPH and al USA 2003 67 569 0 (0) 2 (0.4) (Offit et al. 2003)
3. Pereira and al USA 2004 829 859 9 (1.1) 4(0.5) (Mateus Pereira et al. 2004)
4. Friedrichsen and al USA 2004 506 459 6 (1.2) 2 (0.4) (Friedrichsen et al. 2004)
5. Bernstein and al CANADA 2006 1199 496 18 (1.34) 1 (0.2) (Bernstein et al. 2006)
6. Novak and al CANADA 2008 149 141 3 (2.01) 1 (0.7) (Novak et al. 2008)
7. Shiyu Zhang and al CANADA 2008 560 6460 4 (0.7) 19 (0.3) (Zhang et al. 2008)
8. Gonzalez-Hormazabal and al CHILE 2008 196 1124 0 (0) 0 (0) (Gonzalez-Hormazabal et al. 2008)
9. Shiyu Zhang and al BRAZIL 2008 155 377 1 (0.7) 0 (0) (Zhang et al. 2008)
10. Bell DW LATINAS 2007 362 384 1 0 (0) (Sodha et al. 2007)
Europe        
Sodha and al UNITED KINGDOM 2002 68 300 3(4.4) 0(0) (Sodha et al. 2002)
Check2 Consortium UNITED KINGDOM 2004 2886 3749 35(1.2) 20 (0.53) (CHEK2 Breast Cancer Case–control Consortium CHEK2*1100delC and susceptibility to breast cancer 2004)
Meijers-Heijboer and al UNITED KINGDOM 2002 564 288 7(1.3) 1(0.35) (Meijers-Heijboer et al. 2002)
Meijers-Heijboer and al THE NETHERLANDS 2002 79 460 2(2.5) 6(1.2) (Meijers-Heijboer et al. 2002)
Oldenburg and al THE NETHERLANDS 2003 237 212 27(11.4) 6(2.8) (Oldenburg et al. 2003)
Check2 Consortium THE NETHERLANDS 2004 1706 184 65(3.8) 3(1.6) (CHEK2 Breast Cancer Case–control Consortium CHEK2*1100delC and susceptibility to breast cancer 2004)
De Jong and al THE NETHERLANDS 2005 962 367 28(2.9) 5(1.4) (De Jong et al. 2005)
Offit KPH and al ASHKENAZI JEWISH 2003 33 1096 1(3) 3(0.3) (Offit et al. 2003)
Shiyu Zhang and al JEWISH 2008a 320 180 4(1.3) 0(0) (Zhang et al. 2008)
McInerney and al IRELAND 2009 903 1016 5(0.5) 1(0.1) (McInerney et al. 2009)
Martinez-Bouzas and al BASQUE COUNTRY 2007 214 120 2(0.93) 0(0) (Martınez-Bouzas et al. 2007)
Cybulski and al POLAND 2004a 1017 4000 5(0.5) 10(0.25) (Cybulski et al. 2004)
Cybulski and al POLAND 2007b 4454 5496 20(0.4) 12(0.2) (Cybulski et al. 2007)
Kleibl and al CZECH REPUBLIC 2005 1046 730 4(0.38) 2(0.27) (Kleibl et al. 2005)
Check2 Consortium GERMANY 2004 985 401 11(1.1) 1(0.25) (CHEK2 Breast Cancer Case–control Consortium CHEK2*1100delC and susceptibility to breast cancer 2004)
Dufault and al GERMANY 2004 516 1315 8(1.6) 6(0.5) (Dufault et al. 2004)
Rashid and al GERMANY 2005 613 651 5(0.82) 6(0.92) (Rashid et al. 2005)
Einarsdottir and al SWEDEN 2006 1510 1334 20(0.7) 8(0.4) (Einarsdottir et al. 2006)
Margollin and SWEDEN 2007 450 760 10(2.2) 5(0.7) (Margolin et al. 2007)
Weischer and al DENMARK 2007 1088 4643 13(1.1) 22(0.5) (Weischer et al. 2007)
Vahteristo and al FINLAND 2002 1035 1885 21(2.1) 26 (1.4) (Vahteristo et al. 2002)
Check2 Consortium FINLAND 2004 464 447 13(2.9) 5(1.1) (CHEK2 Breast Cancer Case–control Consortium CHEK2*1100delC and susceptibility to breast cancer 2004)
Kirsi and al FINLAND 2011 82 380 3(0.037) 6(0.016) (Kuusisto Kirsi et al. 2011)
Osorio and al SPAIN 2004 456 400 0(0) 0(0) (Osorio et al. 2004)
Caligo and al ITALY 2004 939 334 1(0.1) 0(0) (Caligo et al. 2004)
Baeyens and al BELGIUM 2005 178 100 4(2.24) 0(0) (Baeyens et al. 2005)
Asia        
Shiyu Zhang and al FILIPINO 2008 342 7 0(0) 0(0) (Zhang et al. 2008)
Chekmariova and al RUSSIA 2006 815 448 22(5.2) 1(0.2) (Chekmariova et al. 2006)
Bell DW JAPANE 2007 428 378 0(0) 0(0) (Sodha et al. 2007)
Rajkumar T and al SOUTH INDIA 2003 22 1 0(0) 0(0) (Rajkumar et al. 2003)
Africa        
Present study MOROCCO 2013 134 114 0(0) 0(0) Present study