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Table 1 Characteristics of individuals with breast cancer at time of diagnosis, screened for the CHEK2 1100delC mutation

From: The CHEK2 1100delC allelic variant is not present in familial and sporadic breast cancer cases from Moroccan population

Characteristics Samples
Cases/Controls 134 / 114
Age at diagnosis, mean ± SD (years) 41 ± 11
Range (years) 23– 67
Menopausal status No. (%)
Premenopausal 76(56.71)
Postmenopausal 57(42.53)
Missing 1(0.74)
Estrogen receptor  
Positive 100 (74.62)
Negative 24(17.91)
Missing 10 (7.46)
Progesterone receptor  
Positive 98 (73.13)
Negative 30(22.38)
Missing 6 (4.47)
Estrogen/Progesterone receptor  
ER + /PR + 66 (49.25)
ER + /PR 15 (11.19)
ER /PR + 10 (7.46)
ER /PR 43 (32.08)
Tumor size  
<2 cm 20 (14.92)
>2 cm 56 (41.79)
>5 cm 31(23.13)
Tumor of any size with extension 27 (20.14)
Histological grade  
1 8 (5.97)
2 87 (64.92)
3 39 (29.10)
Lymph node status  
Negative 56(41.79)
Positive 78 (58.20)
Distant metastases  
Negative 106(79.10)
Positive 28 (20.89)