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Table 2 Severe organ failure, measured with the Sequential Organ Failure Assessment (SOFA) Day 1–5

From: Effects of prostacyclin on the early inflammatory response in patients with traumatic brain injury-a randomised clinical study

Organ system Epoprostenol Placebo  
Respiration 30/111 (27%) 32/113 (28%) ns
Circulation 8/112 (7%) 10/114 (9%) ns
Coagulation 6/114 (5%) 1/112 (1%) ns
Liver function 0 (0%) 0 (0%) ns
Renal function 0 (0%) 0 (0%) ns
  1. Number of days with SOFA ≥3 of all registered SOFA scores on days 1–5 in different organ systems are given in numbers and percentage.
  2. The SOFA scores the degree of organ failure in six different systems (respiratory, haematological, hepatic, cardiovascular, renal, and central nervous system) from zero (no organ failure) to four (severe organ failure). The worst parameter per day in each system was registered without consideration for duration. Severe organ failure is defined here as SOFA ≥3. Central nervous system SOFA was not scored due to the fact that the patients were treated with continuous intravenous sedation.
  3. ns = non-significant.