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Table 4 Heart rate parameters, CCT scan parameters, and image quality in the low-dose landiolol group and the high-dose landiolol group among patients with baseline HR ≥75/min

From: A comparison of bolus injection of landiolol versus oral administration of propranolol before cardiac computed tomography

  Low-dose landiolol High-dose landiolol P value
(n = 77) (n = 92)
HR before β-blocker, min-1 80.3 ± 4.3 79.7 ± 4.1 0.42
Average HR during the main scan, min-1 69.0 ± 6.9 67.2 ± 6.9 0.10
Range of HR during the main scan, min-1 5.3 ± 12.2 5.9 ± 14.9 0.77
Decrease at HR, min-1 11.2 ± 6.0 12.5 ± 6.1 0.18
Time between β-blocker administration and main scan, min 4.1 ± 0.66 3.7 ± 0.80 < 0.001
Helical pitch    0.69
 Step and shoot 0 (0.0%) 0 (0.0%)  
 0.16 72 (93.5%) 86 (93.5%)  
 0.18 3 (3.9%) 5 (5.4%)  
 0.2 0 (0.0%) 0 (0.0%)  
 0.22 0 (0.0%) 0 (0.0%)  
 0.24 2 (2.6%) 1 (1.1%)  
No. of sectors used    0.27
 1 10 (13.0%) 6 (6.5%)  
 2 59 (76.6%) 79 (85.9%)  
 3 8 (10.4%) 7 (7.6%)  
Total exposure, DLP 1582 ± 212 1594 ± 232 0.74
Main scan duration, sec 7.2 ± 0.63 7.5 ± 0.97 0.01
Premature beats during the main scan 6 (7.8%) 6 (6.5%) 0.75
Failure at breathholding 1 (1.3%) 2 (2.2%) 0.67
Presence of coronary artery plaque 32 (41.6%) 51 (55.4%) 0.07
Presence of calcification 53 (68.3%) 73 (79.4%) 0.12
Maximum image quality score per patient    0.02
  1 15 (19.5%) 21 (22.8%)  
  2 14 (18.2%) 28 (30.4%)  
  3 16 (20.8%) 23 (25.0%)  
  4 17 (22.1%) 13 (14.1%)  
  5 15 (19.5%) 7 (7.6%)  
Image quality score per vessel    
 RCA    0.005
  1 19 (24.7%) 30 (32.6%)  
  2 11 (14.3%) 26 (28.3%)  
  3 16 (20.8%) 20 (21.7%)  
  4 21 (27.3%) 10 (10.9%)  
  5 10 (13.0%) 6 (6.5%)  
 LAD    0.054
  1 29 (37.7%) 39 (42.4%)  
  2 13 (16.9%) 32 (34.8%)  
  3 19 (24.7%) 11 (12.0%)  
  4 13 (16.9%) 8 (8.7%)  
  5 3 (3.9%) 2 (2.2%)  
 LCX    0.02
  1 29 (37.7%) 44 (47.8%)  
  2 12 (15.6%) 20 (21.7%)  
  3 10 (13.0%) 17 (18.5%)  
  4 19 (24.7%) 8 (8.7%)  
  5 7 (9.1%) 3 (3.3%)  
  1. CCT, cardiac computed tomography; HR, heart rate; DLP, dose-length product; RCA, right coronary artery; LAD, left anterior descending coronary artery; LCX, left circumflex artery.