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Table 4 Heart rate parameters, CCT scan parameters, and image quality in the low-dose landiolol group and the high-dose landiolol group among patients with baseline HR ≥75/min

From: A comparison of bolus injection of landiolol versus oral administration of propranolol before cardiac computed tomography

 

Low-dose landiolol

High-dose landiolol

P value

(n = 77)

(n = 92)

HR before β-blocker, min-1

80.3 ± 4.3

79.7 ± 4.1

0.42

Average HR during the main scan, min-1

69.0 ± 6.9

67.2 ± 6.9

0.10

Range of HR during the main scan, min-1

5.3 ± 12.2

5.9 ± 14.9

0.77

Decrease at HR, min-1

11.2 ± 6.0

12.5 ± 6.1

0.18

Time between β-blocker administration and main scan, min

4.1 ± 0.66

3.7 ± 0.80

< 0.001

Helical pitch

  

0.69

 Step and shoot

0 (0.0%)

0 (0.0%)

 

 0.16

72 (93.5%)

86 (93.5%)

 

 0.18

3 (3.9%)

5 (5.4%)

 

 0.2

0 (0.0%)

0 (0.0%)

 

 0.22

0 (0.0%)

0 (0.0%)

 

 0.24

2 (2.6%)

1 (1.1%)

 

No. of sectors used

  

0.27

 1

10 (13.0%)

6 (6.5%)

 

 2

59 (76.6%)

79 (85.9%)

 

 3

8 (10.4%)

7 (7.6%)

 

Total exposure, DLP

1582 ± 212

1594 ± 232

0.74

Main scan duration, sec

7.2 ± 0.63

7.5 ± 0.97

0.01

Premature beats during the main scan

6 (7.8%)

6 (6.5%)

0.75

Failure at breathholding

1 (1.3%)

2 (2.2%)

0.67

Presence of coronary artery plaque

32 (41.6%)

51 (55.4%)

0.07

Presence of calcification

53 (68.3%)

73 (79.4%)

0.12

Maximum image quality score per patient

  

0.02

  1

15 (19.5%)

21 (22.8%)

 

  2

14 (18.2%)

28 (30.4%)

 

  3

16 (20.8%)

23 (25.0%)

 

  4

17 (22.1%)

13 (14.1%)

 

  5

15 (19.5%)

7 (7.6%)

 

Image quality score per vessel

   

 RCA

  

0.005

  1

19 (24.7%)

30 (32.6%)

 

  2

11 (14.3%)

26 (28.3%)

 

  3

16 (20.8%)

20 (21.7%)

 

  4

21 (27.3%)

10 (10.9%)

 

  5

10 (13.0%)

6 (6.5%)

 

 LAD

  

0.054

  1

29 (37.7%)

39 (42.4%)

 

  2

13 (16.9%)

32 (34.8%)

 

  3

19 (24.7%)

11 (12.0%)

 

  4

13 (16.9%)

8 (8.7%)

 

  5

3 (3.9%)

2 (2.2%)

 

 LCX

  

0.02

  1

29 (37.7%)

44 (47.8%)

 

  2

12 (15.6%)

20 (21.7%)

 

  3

10 (13.0%)

17 (18.5%)

 

  4

19 (24.7%)

8 (8.7%)

 

  5

7 (9.1%)

3 (3.3%)

 
  1. CCT, cardiac computed tomography; HR, heart rate; DLP, dose-length product; RCA, right coronary artery; LAD, left anterior descending coronary artery; LCX, left circumflex artery.