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Table 3 Heart rate parameters, CCT scan parameters, and image quality in patients receiving low-dose landiolol or propranolol

From: A comparison of bolus injection of landiolol versus oral administration of propranolol before cardiac computed tomography

  Low-dose landiolol Propranolol P value
(n = 188) (n = 277)
HR before β-blocker, min-1 72.9 ± 7.3 72.5 ± 7.7 0.64
Average HR during the main scan, min-1 64.1 ± 7.4 61.6 ± 8.0 <0.001
Range of HR during the main scan, min-1 5.9 ± 14.3 4.4 ± 10.1 0.19
Decrease of HR, min-1 8.8 ± 5.7 11.0 ± 7.2 <0.001
Time between β-blocker administration and main scan, min 4.0 ± 0.6 90.5 ± 16.0 <0.001
Helical pitch    <0.001
 Step and shoot 0 (0.0%) 5 (1.8%)  
 0.16 138 (73.4%) 141 (50.9%)  
 0.18 12 (6.4%) 26 (9.4%)  
 0.2 0 (0.0%) 3 (1.1%)  
 0.22 4 (2.1%) 22 (7.9%)  
 0.24 34 (18.1%) 80 (28.9%)  
No. of sectors used    <0.001
 1 61 (32.5%) 141 (50.9%)  
 2 119 (63.3%) 125 (45.1%)  
 3 8 (4.4%) 11 (4.0%)  
Total exposure, DLP 1450 ± 335 1343 ± 402 0.003
Main scan duration, sec 6.8 ± 1.1 6.4 ± 1.3 <0.001
Premature beats during the main scan 16 (8.5%) 15 (5.4%) 0.19
Failure at breathholding 3 (1.6%) 9 (3.2%) 0.27
Presence of coronary artery plaque 106 (56.3%) 156 (56.3%) 0.99
Presence of calcification 139 (73.9%) 199 (71.8%) 0.62
Maximum image quality score per patient    0.91
 1 55 (29.3%) 88 (31.8%)  
 2 42 (22.3%) 63 (22.7%)  
 3 44 (23.4%) 64 (23.1%)  
 4 29 (15.4%) 42 (15.2%)  
 5 18 (9.6%) 20 (7.2%)  
Image quality score per vessel    
 RCA    0.86
  1 67 (35.6%) 106 (38.3%)  
  2 40 (21.3%) 66 (23.8%)  
  3 38 (20.2%) 50 (18.1%)  
  4 31 (16.5%) 40 (14.4%)  
  5 12 (6.4%) 15 (5.4%)  
 LAD    0.70
  1 87 (46.3%) 132 (47.7%)  
  2 42 (22.3%) 72 (26.0%)  
  3 38 (20.2%) 45 (16.2%)  
  4 16 (8.5%) 19 (6.9%)  
  5 5 (2.7%) 9 (3.2%)  
 LCX    0.32
  1 82 (43.6%) 129 (46.6%)  
  2 44 (23.4%) 69 (24.9%)  
  3 31 (16.5%) 49 (17.7%)  
  4 24 (12.8%) 19 (6.9%)  
  5 7 (3.7%) 11 (4.0%)  
  1. CCT, cardiac computed tomography; HR, heart rate; DLP, dose-length product; RCA, right coronary artery; LAD, left anterior descending coronary artery; LCX, left circumflex artery.