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Table 3 Heart rate parameters, CCT scan parameters, and image quality in patients receiving low-dose landiolol or propranolol

From: A comparison of bolus injection of landiolol versus oral administration of propranolol before cardiac computed tomography

 

Low-dose landiolol

Propranolol

P value

(n = 188)

(n = 277)

HR before β-blocker, min-1

72.9 ± 7.3

72.5 ± 7.7

0.64

Average HR during the main scan, min-1

64.1 ± 7.4

61.6 ± 8.0

<0.001

Range of HR during the main scan, min-1

5.9 ± 14.3

4.4 ± 10.1

0.19

Decrease of HR, min-1

8.8 ± 5.7

11.0 ± 7.2

<0.001

Time between β-blocker administration and main scan, min

4.0 ± 0.6

90.5 ± 16.0

<0.001

Helical pitch

  

<0.001

 Step and shoot

0 (0.0%)

5 (1.8%)

 

 0.16

138 (73.4%)

141 (50.9%)

 

 0.18

12 (6.4%)

26 (9.4%)

 

 0.2

0 (0.0%)

3 (1.1%)

 

 0.22

4 (2.1%)

22 (7.9%)

 

 0.24

34 (18.1%)

80 (28.9%)

 

No. of sectors used

  

<0.001

 1

61 (32.5%)

141 (50.9%)

 

 2

119 (63.3%)

125 (45.1%)

 

 3

8 (4.4%)

11 (4.0%)

 

Total exposure, DLP

1450 ± 335

1343 ± 402

0.003

Main scan duration, sec

6.8 ± 1.1

6.4 ± 1.3

<0.001

Premature beats during the main scan

16 (8.5%)

15 (5.4%)

0.19

Failure at breathholding

3 (1.6%)

9 (3.2%)

0.27

Presence of coronary artery plaque

106 (56.3%)

156 (56.3%)

0.99

Presence of calcification

139 (73.9%)

199 (71.8%)

0.62

Maximum image quality score per patient

  

0.91

 1

55 (29.3%)

88 (31.8%)

 

 2

42 (22.3%)

63 (22.7%)

 

 3

44 (23.4%)

64 (23.1%)

 

 4

29 (15.4%)

42 (15.2%)

 

 5

18 (9.6%)

20 (7.2%)

 

Image quality score per vessel

   

 RCA

  

0.86

  1

67 (35.6%)

106 (38.3%)

 

  2

40 (21.3%)

66 (23.8%)

 

  3

38 (20.2%)

50 (18.1%)

 

  4

31 (16.5%)

40 (14.4%)

 

  5

12 (6.4%)

15 (5.4%)

 

 LAD

  

0.70

  1

87 (46.3%)

132 (47.7%)

 

  2

42 (22.3%)

72 (26.0%)

 

  3

38 (20.2%)

45 (16.2%)

 

  4

16 (8.5%)

19 (6.9%)

 

  5

5 (2.7%)

9 (3.2%)

 

 LCX

  

0.32

  1

82 (43.6%)

129 (46.6%)

 

  2

44 (23.4%)

69 (24.9%)

 

  3

31 (16.5%)

49 (17.7%)

 

  4

24 (12.8%)

19 (6.9%)

 

  5

7 (3.7%)

11 (4.0%)

 
  1. CCT, cardiac computed tomography; HR, heart rate; DLP, dose-length product; RCA, right coronary artery; LAD, left anterior descending coronary artery; LCX, left circumflex artery.