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Table 2 Meta-analysis of the R72P polymorphism of the gene TP53 on breast cancer, by pooling data per continent

From: Association of the TP53 codon 72 polymorphism and breast cancer risk: a meta-analysis

  RR vs. RP RR vs. PP RP vs. PP RR+RP vs. PP RR vs. RP+PP
  OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
Africa 1.41 (0.90-2.22) 1.30 (0.69-2.44) 0.99 (0.54-1.83) 1.05 (0.6-1.86) 1.32 (0.86-2.01)
America 1.04 (0.87-1.23) 1.04 (0.82-1.33) 1.01 (0.88-1.16) 0.98 (0.86-1.11) 0.96 (0.90-1.03)
Asia 1.05 (0.88-1.26) 1.24 (0.87-1.78) 1.15 (0.85-1.57) *1.23 (1.07-1.41) 1.04 (0.93-1.17)
Europe 1.09 (0.97-1.22) 1.10 (0.93-1.31) 1.01 (0.92-1.11) 1.04 (0.95-1.13) 1.03 (0.98-1.08)
Overall 1.01 (0.97-1.04) 1.05 (0.99-1.12) 1.05 (0.99-1.12) 1.06 (0.99-1.12) 1.05 (0.98-1.05)
Heterogeneity χ2 = 3.91 χ2 = 5.42 χ2 = 5.78 χ2 = 6.15 χ2 = 4.53
  P = 0.27 P = 0.14 P = 0.12 P = 0.10 P = 0.21