Figure 2

Histologic spectrum of SALL4-immunopositive hepatocellular carcinoma (HCC). (a) Poorly differentiated HCC with amphophylic cytoplasms. Hematoxylin and eosin (H&E) stain (bar, 100 μm). (b) Poorly differentiated HCC with clear cytoplasms and intracytoplasmic hyaline droplets. H&E stain (bar, 100 μm). (c) Poorly differentiated HCC with small, undifferentiated cells. H&E stain (bar, 100 μm). (d) Moderately differentiated HCC with ductile-like structures. H&E stain (bar, 100 μm). (e) Infiltrative HCC with thin-trabecular growth pattern. Extramedullary hematopoiesis is seen. H&E stain (left bar, 1 mm; right bar, 100 μm). (f) Well differentiated HCC with thin-trabecular architecture and vacuolated cytoplasm. H&E stain (bar, 100 μm).