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Table 3 Clinicopathologic and Recurrence Score results in patients with a treatment change (n = 24)

From: Treatment decisions in estrogen receptor-positive early breast cancer patients with intermediate oncotype DX recurrence score results

 

Type of treatment change

Pre-testing: HT. Post-testing: CHT.

Pre-testing: CHT. Post-testing: HT.

 

(n = 11)

(n = 13)

Age a

  

 Mean (SD), years

54.2 (3.4)

55.1 (9.5)

 Median (range), years

54 (46-58)

56 (35-72)

Tumor size b

  

 Mean (SD), mm

15.6 (5.7)

20.4 (7.6)

 Median (range), mm

14 (10-28)

20.5 (10-32)

Nodal status, c n (%)

  

 Node negative

10 (100)

8 (72.7)

 Node positive

0 (0)

3 (27.3)

Tumor grade, d n (%)

  

 1

1 (9.1)

0 (0)

 2

8 (72.7)

7 (63.6)

 3

2 (18.2)

4 (36.4)

Type of surgery, e n (%)

  

 Lumpectomy

10 (90.9)

9 (69.2)

 Mastectomy

1 (9.1)

4 (30.8)

Recurrence Score result f

  

 Mean (SD)

27.3 (1.7)

21.1 (3.0)

 Median (range)

28 (23-29)

20 (18-28)

  1. CHT chemohormonal therapy; HT hormonal therapy; SD standard deviation.
  2. aP = 0.76 (t-test for comparing means).
  3. bP = 0.11 (t-test for comparing means). Tumor size information was unavailable for 1 patient in the chemohormonal to hormonal therapy group.
  4. cP = 0.21 (Fisher’s exact test). Nodal status information was unavailable for 1 patient in the hormonal therapy to chemohormonal therapy group and 2 patients in the chemohormonal to hormonal therapy group.
  5. dP = 0.64 (Fisher’s exact test). Grade information was unavailable for 2 patients in the chemohormonal to hormonal therapy group.
  6. eP = 0.33 (Fisher’s exact test).
  7. fP = 0.0014 (MWW test).
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