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Table 5 Multivariable analysis of breast cancer mortality in invasive lobular carcinoma a

From: Invasive lobular carcinoma of the breast: long-term prognostic value of Ki67 and histological grade, alone and in combination with estrogen receptor

Prognostic factor n # events HR 95% CI p-value
Age (years) 161 52 0.98 0.96-1.01 0.29
Tumour size (mm)      
  ≤20 93 21 1.0   
  >20 68 31 1.8 0.91-3.7 0.09
Nodal status (p <0.001)b      
  0 100 25 1.0   
  1-3+ 27 7 0.88 0.35-2.2 0.78
  >3+ 34 20 4.0 1.8-8.5 <0.001
Histological grade (p = 0.08)b      
  1 25 5 1.1 0.41-3.0 0.83
  2 124 41 1.0   
  3 12 6 3.2 1.2-8.7 0.02
ER      
  + 141 42 1.0   
  - 20 10 1.1 0.52-2.4 0.77
PgR      
  + 87 25 1.0   
  - 74 27 1.3 0.76-2.4 0.31
Ki67 (p = 0.36)b      
  0-10% 92 25 1.0   
  11-30% 57 21 1.3 0.72-2.5 0.36
  >30% 12 6 2.0 0.73-5.5 0.18
  1. aAdjusted for adjuvant treatment.
  2. b2-degree-of-freedom test of no factor effect.