|
Prognostic factor
|
n
|
# events
|
HR
|
95% CI
|
p-value
|
|---|
|
Age (years)
|
161
|
52
|
0.98
|
0.96-1.01
|
0.29
|
|
Tumour size (mm)
| | | | | |
|
≤20
|
93
|
21
|
1.0
| | |
|
>20
|
68
|
31
|
1.8
|
0.91-3.7
|
0.09
|
|
Nodal status (p <0.001)b
| | | | | |
|
0
|
100
|
25
|
1.0
| | |
|
1-3+
|
27
|
7
|
0.88
|
0.35-2.2
|
0.78
|
|
>3+
|
34
|
20
|
4.0
|
1.8-8.5
|
<0.001
|
|
Histological grade (p = 0.08)b
| | | | | |
|
1
|
25
|
5
|
1.1
|
0.41-3.0
|
0.83
|
|
2
|
124
|
41
|
1.0
| | |
|
3
|
12
|
6
|
3.2
|
1.2-8.7
|
0.02
|
|
ER
| | | | | |
|
+
|
141
|
42
|
1.0
| | |
|
-
|
20
|
10
|
1.1
|
0.52-2.4
|
0.77
|
|
PgR
| | | | | |
|
+
|
87
|
25
|
1.0
| | |
|
-
|
74
|
27
|
1.3
|
0.76-2.4
|
0.31
|
|
Ki67 (p = 0.36)b
| | | | | |
|
0-10%
|
92
|
25
|
1.0
| | |
|
11-30%
|
57
|
21
|
1.3
|
0.72-2.5
|
0.36
|
|
>30%
|
12
|
6
|
2.0
|
0.73-5.5
|
0.18
|
- aAdjusted for adjuvant treatment.
- b2-degree-of-freedom test of no factor effect.
