Table 5 Multivariable analysis of breast cancer mortality in invasive lobular carcinoma a
Prognostic factor | n | # events | HR | 95% CI | p-value |
|---|---|---|---|---|---|
Age (years) | 161 | 52 | 0.98 | 0.96-1.01 | 0.29 |
Tumour size (mm) | |||||
≤20 | 93 | 21 | 1.0 | ||
>20 | 68 | 31 | 1.8 | 0.91-3.7 | 0.09 |
Nodal status (p <0.001)b | |||||
0 | 100 | 25 | 1.0 | ||
1-3+ | 27 | 7 | 0.88 | 0.35-2.2 | 0.78 |
>3+ | 34 | 20 | 4.0 | 1.8-8.5 | <0.001 |
Histological grade (p = 0.08)b | |||||
1 | 25 | 5 | 1.1 | 0.41-3.0 | 0.83 |
2 | 124 | 41 | 1.0 | ||
3 | 12 | 6 | 3.2 | 1.2-8.7 | 0.02 |
ER | |||||
+ | 141 | 42 | 1.0 | ||
- | 20 | 10 | 1.1 | 0.52-2.4 | 0.77 |
PgR | |||||
+ | 87 | 25 | 1.0 | ||
- | 74 | 27 | 1.3 | 0.76-2.4 | 0.31 |
Ki67 (p = 0.36)b | |||||
0-10% | 92 | 25 | 1.0 | ||
11-30% | 57 | 21 | 1.3 | 0.72-2.5 | 0.36 |
>30% | 12 | 6 | 2.0 | 0.73-5.5 | 0.18 |