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Table 1 Patient and tumour characteristics ( n =192)

From: Invasive lobular carcinoma of the breast: long-term prognostic value of Ki67 and histological grade, alone and in combination with estrogen receptor

Variables

No (%)

Age (years)

 

  Median (range)

62 (36–87)

Menopausal status

 

  Premenopausal

48 (26)

  Postmenopausal

138 (74)

  Unknown

6

Type of surgery

 

  BCSa (no ALNDb)

4 (2)

  BCS + ALND

36 (19)

  Mastectomy (no ALND)

7 (4)

  Mastectomy + ALND

145 (76)

Tumour size (mm)

 

  pT1 (≤20)

108 (57)

  pT2 (>20 and ≤50)

69 (37)

  pT3 (>50)

12 (6)

  Undefined

3

Nodal status c

 

  pN- (ALND)

106 (59)

  cN- (no ALND)

11

  pN+

75 (41)

  pN1 (1-3+)

36 (20)

  pN2 (4-9+)

28 (16)

  pN3 (>9+)

11 (6)

Pathological stage d

 

  I

78 (42)

  II

68 (36)

  III

42 (22)

  IV

0 (0)

  Undefined (but not stage IV)

4

Adjuvant therapy e

 

  RT (total)

93 (48)

  CT (total)

5 (3)

  ET (total)

78 (41)

  RT (monotherapy)

39 (20)

  CT (monotherapy)

3 (12)

  ET (monotherapy)

27 (14)

  RT+CT

3 (2)

  RT+ET

51 (27)

  CT+ET

0 (0)

  RT+CT+ET

0 (0)

  1. aBCS: Breast conserving surgery.
  2. bALND: Axillary lymph node dissection.
  3. cc = clinical, p = pathological, N- = node negative, N+ = node positive.
  4. dPathological stage: I = pT1-2N0M0, II = T2-3N0, M0 T1-2N1M0,
  5. III = pT3N1M0, pT1-3N2M0, T4N0-2M0, T1-4N3M0,
  6. IV = T1-4N0-3M1.
  7. eAdjuvant therapy: RT = radiotherapy, CT = chemotherapy, ET = endocrine therapy.