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Table 4 Univariate analysis of imaging findings of ccRCC and Fuhrman grades

From: Tumor grade of clear cell renal cell carcinoma assessed by contrast-enhanced computed tomography

  Grades 1-2 Grades 3-4 P-value
Calcification* +/- (n = 214) 10/106 24/74 0.0023
Tumor heterogeneity Homo/Hetero (n = 192) 8/89 8/87 1.0
Non-enhancing area ≥60%/<60% (n = 192) 15/82 27/68 0.036
  1. Note. The data show the number of the lesions. The heterogeneity of the lesions (homogeneous or heterogeneous) and the percentage of non-enhancing (necrotic) area were evaluated in the predominantly solid ccRCC (n = 192). The presence or absence of calcification was evaluated in total ccRCC cases (n = 214).
  2. *Calcification is significantly more common in grades 3–4 than grades 1–2. Non-enhancing area 60% or more within the predominantly solid clear cell renal cell carcinoma is significantly more common in grades 3–4 than grades 1–2.