Figure 1
From: Interactions of antiparasitic sterols with sterol 14α-demethylase (CYP51) of human pathogens
Docking energies (re-rank score) of antiparasitic sterols in L. infantum drug targets (Sterol 14 α demethylase (CYP51), glyoxalase II (GLO2), thiol-dependent reductase I (TDR1), trypanothione reductase (TR). The figure shows the selectivity of sterol-like compounds for CYP51. One—way ANOVA followed by Tukey’s multiple comparison test suggest statistically significant difference between the means of all groups (P < 0.0001).