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Table 3 Positive findings in patients and multivariate analysis of statistically significant positive findings

From: Novel uterine sarcoma preoperative diagnosis score predicts the need for surgery in patients presenting with a uterine mass

 

Total

Sarcoma

Benign

p-value(sar. vs. ben.)

Sensitivity

Specificity

PPV (%)

NPV (%)

Age (≥49)

31/63 (49.2%)

14/15 (93.3%)

17/48 (35.4%)

<0.001*

0.93

0.65

45.2

96.9

Serum CA125 (≥35)

17/63 (27.0%)

6/15 (40.0%)

11/48 (22.9%)

0.193

0.40

0.77

35.3

80.4

Serum LDH (≥279)

7 /63(11.1%)

7/15 (46.7%)

0/48 (0.0%)

<0.001*

0.47

1.00

100.0

85.7

RI (≤0.4)

28/63 (44.4%)

7/15 (46.7%)

29/48 (60.4%)

0.348

0.47

0.40

19.4

70.4

MRI findings

27/63 (42.9%)

12/15 (80.0%)

15/48 (31.3%)

<0.001*

0.80

0.69

44.4

91.7

Cytological findings

6/63 (9.5%)

5/15 (33.37%)

1/48 (2.1%)

<0.001*

0.33

0.93

83.3

58.3

<multivariate analysis>

odds ratio

95% CI

p-value

     

Age

7.001×107

[3.700, >1000]

0.003*

     

Serum LDH

2.304×109

[15.775, >1000]

<0.001*

     

MRI findings

0.420

[0.014, 4.604]

0.499

     

Cytological findings

4.784×108

[19.554, >1000]

<0.001*

     
  1. *P <0.05.