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Figure 5 | SpringerPlus

Figure 5

From: LTC4 synthase polymorphism modifies efficacy of botanical seed oil combination in asthma

Figure 5

Effects of dietary supplementation with borage and echium seed oils on 5-LO pathway product formation by ionophore-stimulated peripheral blood granulocyte fractions from stable asthmatic subjects with AA and AC/CC LTC4S genotypes. a. Sum of total 5-LO pathway products (5-HETE, all-trans-LTB4, LTB4, and cys-LTs) generated per 1 × 106 ionophore-stimulated granulocytes in each indicated genotype after 3 and 6 weeks of treatment on each arm. b. Non-cys LTs (5-HETE, all-trans- LTB4, LTB4) c. cys-LTs (LTC4, LTD4, and LTE4) were measured for the same samples.

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