Cigarette smoking and breast cancer risk in relation to joint estrogen and progesterone receptor status: a case-control study in Japan

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Table 6 Odds ratio (OR) according to passive smoking by menopausal and hormone receptor status

	Premenopausal^a												Postmenopausal^b
	Controls	ER+/PgR+ (n = 166)					ER-/PgR- (n = 63)					P _{heterogeneity}		ER+/PgR+ (n = 262)					ER-/PgR- (n = 137)					P _{heterogeneity}
	Controls	Cases	OR	95% CI			Cases	OR	95% CI			P _{heterogeneity}	Controls	Cases	OR	95% CI			Cases	OR	95% CI			P _{heterogeneity}
Passive smoking (husband’s smoking)
Never smoker	158	54	1 (Reference)				21	1 (Reference)					547	90	1 (Reference)				48	1 (Reference)
Current	288	81	0.96	0.61	-	1.52	35	0.96	0.51	-	1.81		486	85	1.19	0.85	-	1.68	52	1.28	0.83	-	1.97
Past	105	31	0.76	0.42	-	1.37	7	0.53	0.20	-	1.38		363	87	1.31	0.93	-	1.84	37	1.02	0.64	-	1.63
Ever	393	112	0.90	0.59	-	1.39	42	0.85	0.46	-	1.56	0.86	849	172	1.25	0.93	-	1.68	89	1.16	0.79	-	1.70	0.74
Analyzed for never-smoking married women.

^aAdjusted by age, BMI, occupation, physical activity, age at menarche, age at first birth, family history of breast cancer in mother or sister, parity number, use of exogenous female hormone or oral contraceptives, referrel status, year of recruitment, area of residence and alcohol drinking.
^bAdjusted by age, BMI, occupation, physical activity, age at menarche, age at menopause, reson of menopause (natural, others including surgery), age at first birth, family history of breast cancer in mother or sister, parity number, use of exogenous female hormone or oral contraceptives, referrel status, year of recruitment, area of residence and alcohol drinking.