Figure 6From: Lysine suppresses myofibrillar protein degradation by regulating the autophagic-lysosomal system through phosphorylation of Akt in C2C12 cellsEffect of Lys and/or AICAR treatment on myofibrillar protein degradation in C2C12 myotubes. Cells were incubated in medium containing DMSO (C), 1 mM AICAR (Ac), 10 mM Lys (K), or 10 mM Lys and 1 mM AICAR (AcK) for 4 h. MeHis released from the cells was measured by HPLC. Values are means with SE (n = 3). Different letters indicate significant differences among the groups (p < 0.05).Back to article page