Figure 1From: Increased expression of CYP17A1 indicates an effective targeting of the androgen receptor axis in castration resistant prostate cancer (CRPC)Expression profile of PSA and TMPRSS2-ERG: VCaP and LNCaP showing decreased PSA and TMPRSS2-ERG (VCaP) mRNA expression after treatment with with 5, 10 or 25 μM AA (A-C). In addition treatment with 10 μM AA leads to a decreased PSA secretion in VCaP (D); (* = p < 0.05, ** = p < 0.005 and *** = p < 0.0005).Back to article page