Systemic levels of the endothelium-derived soluble adhesion molecules endocan and E-selectin in patients with suspected deep vein thrombosis

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Table 2 Comparison of serum CRP, plasma endocan and plasma E-selectin levels (luminex analyses, the 89 first consecutive patients) in patients admitted to hospital with suspected deep vein thrombosis

	Thrombophlebitis	Sterile inflammation	Infection	Venous stasis	Other causes without inflammation
ENDOCAN LEVELS - COMPARISON BETWEEN VARIOUS PATIENT SUBSETS (n = 117)
Deep vein thrombosis (n = 28)	0.5723	0.0407	0.8479	0.1058	0.1066
Thrombophlebitis (n = 6)		0.6558	0.3736	0.2284	0.5725
Sterile inflammation (n = 30)			0.0818	0.0230	0.8742
Infection (n = 12)				0.1770	0.1435
Venous stasis (n = 8)					0.0230
Other causes without inflammation (n = 33)					0.0230
E-SELECTIN LEVELS - COMPARISON BETWEEN VARIOUS PATIENT SUBSETS (n = 89)
Deep vein thrombosis (n = 21)	0.7450	0.2485	0.0517	0.4208	0.5618
Thrombophlebitis (n = 5)		0.8271	0.1898	0.4351	0.8852
Sterile inflammation (n = 22)			0.0938	0.9813	0.5165
Infection (n = 9)				0.2359	0.0499
Venous stasis (n = 8)					0.5864
Other causes without inflammation (n = 24)					0.5864
CRP LEVELS - COMPARISON BETWEEN VARIOUS PATIENT SUBSETS (n = 120)
Deep vein thrombosis (n = 28)	0.2132	0.0842	0.1693	0.1949	< 0.0001
Thrombophlebitis (n = 6)		0.7993	0.0608	0.8461	0.1396
Sterile inflammation (n = 33)			0.0097	1.0000	0.0029
Infection (n = 12)				0.0277	< 0.0001
Other causes without inflammation (n = 33)				0.0277	< 0.0001

The Mann Whitney t-test was used for the statistical comparison and the p-value is given for each statistical comparison (significant differences are marked in bold). Thrombophlebitis was defined as clinical signs of a local inflammatory reaction corresponding to a subcutaneous vein of the affected limb, infection means clinical and laboratory evidence for a local infection corresponding to the affected the lower limb, and sterile inflammation means a condition with local sterile inflammation of the affected limb (e.g. a ruptured Baker’s cyst).