Figure 1

Comparison between the mean ages of onset (±95% CI) of CAD among several groups of CAD patients sorted according to the associated risk factors (RF). CAD patients within the group “hypertension” had only hypertension as RF. The group “no RF” had no observed or documented RF. A. CAD age of onset in non-hypertensive patients with cumulative RF was compared between the various CAD groups (ANOVA) and then each group to the “hypertension” group (Tukey HSD). CAD patients within group “no hypertension + 1 RF” had any of the following RF: smoking, obesity, diabetes, hyperlipidemia and FxCAD, but did not have hypertension. In subsequent groups, CAD patients had any two, three, four or all five RF, but no hypertension. (*p < 0.05, **p < 0.01, ***p < 0.001 vs. hypertension group). B. CAD age of onset in hypertensive patients with cumulative RF was compared between the various CAD groups and then each group to the “hypertension” group. CAD patients in group “hypertension + 1 RF” had hypertension in addition to anyone of the other previously mentioned RF. In subsequent groups, CAD patients with hypertension had any two, three, four or all five additional RF. HSD (*p < 0.05, **p < 0.01, ***p < 0.001 vs. hypertension group).