Figure 4

Distribution of delay (days) in treatment with intravenous ACV from the onset of symptoms (y-axis) compared to prognosis after HSE (x-axis). The OR of being in Karnofsky performance scale (KPS) category 2 and 3 vs. KPS category 1 for each day of delay is 0.76 (95% CI 0.55–0.94p = 0.04). Black dots indicate patients who died within a year from admission. *1 = 0–40% performance. 2 = 50–70% performance. 3 = 80–100% performance.