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Table 2 Relationship between allele and genotypes of T869C and protein expression of TGFβ1 or urinary TGF-β1 levels

From: Changes to signal peptide and the level of transforming growth factor- β1 due to T869C polymorphism of TGF β1 associated with lupus renal fibrosis

 

Urinary TGFβ1 levels (pg/ml)

Protein expression of TGFβ1 in renal tissues (%)

  

Case group

Control group

p value

Case group

Control group

p value

  

(n = 45)

(n = 45)

 

(n = 35)

(n = 10)

 

Allele

T

48.99 ± 28.89

24.87 ± 9.9

< 0.01

52.68 ± 21.13

49.69 ± 26.69

<0.01

 

C

78.83 ± 116.66

19.99 ± 8.37

<0.01

56.51 ± 22.42

23.57 ± 6.72

<0.01

Genotype

TT

46.75 ± 21.64

24.79 ± 10.48

0.03

47.00 ± 21.02

17.60 ± 7.12

0.14

 

TC

52.57 ± 38.83

25.47 ± 6.76

0.01

63.20 ± 14.68

26.0 ± 14.71

0.01

 

CC

89.78 ± 137.71

16.86 ± 8.04

<0.01

54.60 ± 25.01

27.00 ± 7.07

0.15

  1. Note: Values present as mean ± standard deviations, %: percentage, p-value of <0.05: significant difference.