Figure 2
From: The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma
DR5 overexpression does not enhance TRAIL-induced apoptosis in U87 cells. (A) Flow cytometry analysis was performed on U87-control and U87-DR5 cells to measure the cell surface expression of TRAIL receptors DR4 and DR5, expressed as the Mean Fluorescence Intensity (MFI) ratio. A172 cells were used as a control. (B) Cell viability was assessed after 24h treatment with 0–1000 ng/ml rhTRAIL WT or D269H/E195R using MTS assays. Presented data are representative for three independent experiments and mean cell viability levels ± S.E.M. are shown.