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Figure 1 | SpringerPlus

Figure 1

From: The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma

Figure 1

A172 cells are sensitive to TRAIL-induced apoptosis in a dose-dependent manner. (A) Cell surface expression of the various TRAIL receptors was determined on A172 and U87 cells using flow cytometry analysis and expressed as the Mean Fluorescence Intensity (MFI) ratio. (B) Viability of A172 and U87 cells was assessed after treatment with various concentrations (0–1000 ng/ml) of rhTRAIL WT, 4C7 or D269H/E195R for 24h as measured by MTS assays. (C) Western blot analysis of A172 and U87 cells treated with 0, 10 or 100 ng/ml rhTRAIL WT for 5h or 24h, respectively. β-actin serves as a loading control. Error bars represent S.E.M. of three independent experiments.

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