Table 2 Clinical outcomes stratified by study group
From: A comparison of three dose timings of methylprednisolone in infant cardiopulmonary bypass
Variable (mean) | Ultra-early group (n = 18) | Early group (n = 17) | Standard group (n = 19) | p* |
|---|---|---|---|---|
Weight (kg) | ||||
Pre-operative (SD) | 3.73 (0.84) | 3.65 (1.30) | 4.60 (2.27) | >0.05 |
24 hours after surgery (SD) | 4.20 (0.85) | 4.23 (1.65) | 4.74 (1.91) | >0.05 |
48 hours after surgery (SD) | 4.15 (0.85) | 4.10 (1.47) | 5.10 (2.11) | >0.05 |
72 hours after surgery (SD) | 4.00 (0.87) | 3.94 (1.36) | 5.06 (2.11) | >0.05 |
Urinary output (ml/kg/h) | ||||
24 hours (SD) | 1.47 (0.64) | 1.27 (0.62) | 1.36 (0.68) | >0.05 |
48 hours (SD) | 4.41 (1.47) | 4.58 (1.73) | 3.43 (1.32) | 0.047δ and 0.037Ψ |
72 hours (SD) | 5.24 (1.69) | 5.56 (2.08) | 4.71 (1.31) | >0.05 |
Balance (ml/kg/day) | ||||
24 hours (SD) | 61.47 (39.48) | 46.50 (40.36) | 57.13 (70.43) | >0.05 |
48 hours (SD) | –34.66 (47.60) | -33.94 (48.73) | -11.63 (35.40) | >0.05 |
72 hours (SD) | -54.53 (47.80) | -53.50 (44.55) | -36.28 (31.20) | >0.05 |
Inotrope score | ||||
24 hours (SD) | 16.41 (6.39) | 13.96 (14.86) | 11.81 (25.11) | >0.05 |
48 hours (SD) | 17.71 (6.23) | 13.12 (10.27) | 9.25 (24.68) | >0.05 |
72 hours (SD) | 18.33 (5.05) | 15.66 (6.83) | 13.80 (24.58) | >0.05 |
MV duration (days, SD) | 6.30 (3.51) | 5.65 (4.18) | 4.94 (3.62) | >0.05 |
PICU LOS (days, SD) | 11.82 (11.77) | 11.24 (9.10) | 9.17 (5.65) | >0.05 |
Death (%) | 1 (0.06) | 1 (0.06) | 1 (1.19) | >0.05 |