Skip to main content

Table 4 Regression models with falls as dependent variable

From: Medication and falls in elderly outpatients: an epidemiological study from a German Pharmacovigilance Network

 

Model 1

Model 2

Model 3

Final Model

 

AOR (95% CI)

Crude OR (95% CI)

p value

AOR (95% CI)

p value

AOR (95% CI)

p value

AOR (95% CI)

p value

Age in years

1.024(1.012-1.036)

 

<0.001

1.01.0(0.997-1.024)

<=0.15

1.011.0(0.998-1.024)

<=0.15

1.013(1.001-1.026)

<0.05

Female gender

1.1(0.9-1.4)

 

>0.15

1.0(0.8-1.3)

>0.15

1.0(0.8-1.3)

>0.15

1.0(0.8-1.3)

0.675

Abnormalities of gait and mobility (incl. parkinson)

 

2.6(1.6-4)

<0.001

2.1(1.3-3.3)

<0.05

2.0(1.2-3.2)

<0.05

2.1(1.3-3.4)

<0.05

Arthritis

 

2.0(1.6-2.5)

<0.001

1.5(1.2-1.9)

<0.001

1.4(1.1-1.8)

<0.05

1.5(1.2-1.9)

<0.001

Cerebovascular disease

 

1.8(1.3-2.5)

<0.001

1.3(0.9-1.9)

<=0.15

1.4(0.9-1.9)

<0.1

-

-

Chronic ischaemic heart disease

 

1.1(0.8-1.5)

>0.15

-

-

-

-

-

-

Dementia

 

1.8(1.2-2.6)

<0.05

1.3(0.8-1.9)

>0.15

-

-

-

-

Depression

 

2.0(1.5-2.5)

<0.001

1.4(1.1-1.9)

<0.05

1.3(1.0-1.7)

<0.1

-

-

Diabetes

 

1.3(1.0-1.7)

<0.1

1.1(0.8-1.4)

>0.15

-

-

-

-

Disability in moving

 

1.1(0.7-1.7)

>0.15

-

-

-

-

-

-

Diseases of arteries, arterioles and capillaries

 

1.9(1.6-2.4)

<0.001

1.4(1.1-1.8)

<0.05

1.4(1.1-1.8)

<0.05

1.5(1.2-1.9)

<0.001

Hearing impaiment

 

2.9(1.7-4.7)

<0.001

1.6(0.9-2.8)

<0.1

1.7(1.0-2.8)

<0.1

-

-

Heart failure

 

2.2(1.6-2.8)

<0.001

1.6(1.2-2.1)

<0.05

1.6(1.2-2.1)

<0.05

1.7(1.3-2.3)

<0.001

Hypertension

 

1.3(1.0-1.6)

<0.05

1.1.0(0.9-1.4)

>0.15

-

-

-

-

Incontinence

 

1.9(1.3-2.5)

<0.001

1.3(0.9-1.8)

<=0.15

1.3(0.9-1.8)

<=0.15

-

-

Intervertebral disc disorders, dorsalgia

 

1.8(1.4-2.3)

<0.001

1.3(1.0-1.7)

<0.05

1.2(0.9-1.6)

<=0.15

-

-

Malignant neoplasm

 

0.6(0.5-0.8)

<0.001

-

-

-

-

-

-

Osteoporose

 

0.9(0.2-2.6)

>0.15

-

-

-

-

-

-

Sleep disorders

 

2.1(1.5-2.8)

<0.001

1.5(1.0-2.0)

<0.05

1.4(1.0-1.9)

<0.1

-

-

Vertigo

 

3.7(2.5-5.4)

<0.001

2.5(1.6-3.8)

<0.001

2.5(1.6-3.7)

<0.001

2.9(1.9-4.2)

<0.001

Visual impairment

 

3.4(1.9-5.5)

<0.001

1.9(1.0-3.3)

<0.05

1.9(1.0-3.3)

<0.05

2.1(1.2-3.6)

<0.05

Weight loss

 

3.6(1.4-8.2)

<0.05

2.9(1.1-6.7)

<0.05

2.8(1.1-6.6)

<0.05

3.1(1.2-7.1)

<0.05

Fall risk increasing drugs (FRIDS)

  

<0.001

-

-

1.5(1.2-1.9)

<0.001

1.7(1.4-2.1)

<0.001

  1. Regression models with falls as dependent variable: Model 1 age and sex. Each fall-related chronic diseases, was tested as a risk factor adjusted for age and sex. Model 2 included all fall-related chronic diseases with a p value < 0.15 adjusted for age and sex and an OR >1. Model 3, including FRIDS and all fall-related chronic diseases from Model 2 with a p value < 0.15 adjusted for age and sex.