Figure 4

Principal components analysis ( score plot of PC1 vs. PC3) from different cell lines (first letter “ G ” and “ N ” means G2 and N3 , respectively) submitted in two different conditions of oxygen tension (second letter “ h ” and “ n ” means hypoxia and normoxia, respectively) and glucose levels (third letter “ h ” and “ c ” means high and control, respectively), corresponding to 8 mean values of each triplicate. To facilitate the visualization of results, the open symbols represent the G2 and solid represent N3 lines. Key: ● Nhh, ○ Ghh, ■ Nhc, □ Ghc, ▲ Nnh, ∆ Gnh, ♦ Nnc and ⋄ Gnc.