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Table 5 Patient whole brain and ROI grey matter volume correlations with cognitive domains

From: A prospective study of grey matter and cognitive function alterations in chemotherapy-treated breast cancer patients

Region Processing speed Working memory Verbal memory Visual memory
  r t(18) p value r t(18) p value r t(18) p value r t(18) p value
Composite Whole-Brain 0.61 4.75 <0.001 0.01 0.09 0.933 0.05 0.16 0.877 0.18 0.85 .407
Left Hemisphere             
Medial Orbitofrontal Gyrus 0.36 4.27 <0.001 0.51 3.05 0.007 -0.35 -1.20 0.244 0.19 0.88 0.393
Inferior Orbitofrontal Gyrus 0.36 3.91 0.001 0.12 0.75 0.461 -0.63 -1.81 0.088 -0.18 -0.75 0.461
Inferior Frontal Operculum 0.54 3.15 0.006 0.42 2.11 0.049 0.48 1.25 0.229 0.71 2.91 0.009
Middle Temporal Gyrus 0.21 1.29 0.213 -0.02 -0.15 0.883 0.24 0.76 0.457 0.14 0.63 0.540
Insular Cortex 0.44 4.21 <0.001 -0.07 -0.43 0.672 -0.10 -0.27 0.789 0.05 0.21 0.837
Superior Temporal Gyrus 0.56 4.56 <0.001 0.17 0.01 0.948 0.09 0.29 0.775 0.05 0.22 0.829
Anterior Cingulate 0.35 2.25 0.037 0.12 0.91 0.376 0.04 0.11 0.917 0.31 1.39 0.180
Calcarine Cortex 0.26 2.55 0.020 -0.01 -0.09 0.929 0.15 0.48 0.640 0.13 -0.56 0.582
Right Hemisphere             
Middle Frontal Gyrus 0.54 3.15 0.006 0.42 2.11 0.049 0.48 1.25 0.229 0.72 2.91 0.009
Gyrus Rectus 0.14 0.94 0.359 0.09 0.56 0.582 0.15 1.25 0.229 0.32 1.50 0.150
Paracentral Lobule 0.58 3.86 0.001 0.14 -0.85 0.408 0.04 0.15 0.886 -0.02 -0.09 0.932
Precuneus 0.19 1.25 0.227 -0.04 -0.38 0.709 0.13 0.39 0.698 0.16 0.59 0.564
Hippocampus 0.26 1.95 0.066 0.10 0.88 0.393 -0.12 -0.40 0.696 -0.08 -0.36 0.721
Anterior Cingulate 0.01 0.09 0.933 0.07 0.56 0.585 -0.15 -0.46 0.653 0.13 0.57 0.577
  1. n = 19.