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Table 5 Patient whole brain and ROI grey matter volume correlations with cognitive domains

From: A prospective study of grey matter and cognitive function alterations in chemotherapy-treated breast cancer patients

Region

Processing speed

Working memory

Verbal memory

Visual memory

 

r

t(18)

p value

r

t(18)

p value

r

t(18)

p value

r

t(18)

p value

Composite Whole-Brain

0.61

4.75

<0.001

0.01

0.09

0.933

0.05

0.16

0.877

0.18

0.85

.407

Left Hemisphere

            

Medial Orbitofrontal Gyrus

0.36

4.27

<0.001

0.51

3.05

0.007

-0.35

-1.20

0.244

0.19

0.88

0.393

Inferior Orbitofrontal Gyrus

0.36

3.91

0.001

0.12

0.75

0.461

-0.63

-1.81

0.088

-0.18

-0.75

0.461

Inferior Frontal Operculum

0.54

3.15

0.006

0.42

2.11

0.049

0.48

1.25

0.229

0.71

2.91

0.009

Middle Temporal Gyrus

0.21

1.29

0.213

-0.02

-0.15

0.883

0.24

0.76

0.457

0.14

0.63

0.540

Insular Cortex

0.44

4.21

<0.001

-0.07

-0.43

0.672

-0.10

-0.27

0.789

0.05

0.21

0.837

Superior Temporal Gyrus

0.56

4.56

<0.001

0.17

0.01

0.948

0.09

0.29

0.775

0.05

0.22

0.829

Anterior Cingulate

0.35

2.25

0.037

0.12

0.91

0.376

0.04

0.11

0.917

0.31

1.39

0.180

Calcarine Cortex

0.26

2.55

0.020

-0.01

-0.09

0.929

0.15

0.48

0.640

0.13

-0.56

0.582

Right Hemisphere

            

Middle Frontal Gyrus

0.54

3.15

0.006

0.42

2.11

0.049

0.48

1.25

0.229

0.72

2.91

0.009

Gyrus Rectus

0.14

0.94

0.359

0.09

0.56

0.582

0.15

1.25

0.229

0.32

1.50

0.150

Paracentral Lobule

0.58

3.86

0.001

0.14

-0.85

0.408

0.04

0.15

0.886

-0.02

-0.09

0.932

Precuneus

0.19

1.25

0.227

-0.04

-0.38

0.709

0.13

0.39

0.698

0.16

0.59

0.564

Hippocampus

0.26

1.95

0.066

0.10

0.88

0.393

-0.12

-0.40

0.696

-0.08

-0.36

0.721

Anterior Cingulate

0.01

0.09

0.933

0.07

0.56

0.585

-0.15

-0.46

0.653

0.13

0.57

0.577

  1. n = 19.