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Figure 1

From: Severe experimental folate deficiency in a human subject – a longitudinal study of biochemical and haematological responses as megaloblastic anaemia develops

Figure 1

Changes in folate and energy intake, and body weight over time. A. Folate intake. B. Energy intake. C. Weight. Severe dietary folate deficiency commenced on Day 0 (23 May 2011). The folate-replete diet, with folate supplementation, resumed on day 586 (29 December 2012), and recovery was complete on day 772 (3 July 2013). The dotted line in panel A is the recommended daily intake for folate (Institute of Medicine, National Academy of Sciences 1998). The dotted line in panel B is the initial estimated daily energy requirement for the subject (Australian Government National Health and Medical Research Council 2013a).

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