Figure 1From: Severe experimental folate deficiency in a human subject – a longitudinal study of biochemical and haematological responses as megaloblastic anaemia developsChanges in folate and energy intake, and body weight over time. A. Folate intake. B. Energy intake. C. Weight. Severe dietary folate deficiency commenced on Day 0 (23 May 2011). The folate-replete diet, with folate supplementation, resumed on day 586 (29 December 2012), and recovery was complete on day 772 (3 July 2013). The dotted line in panel A is the recommended daily intake for folate (Institute of Medicine, National Academy of Sciences 1998). The dotted line in panel B is the initial estimated daily energy requirement for the subject (Australian Government National Health and Medical Research Council 2013a).Back to article page