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Table 2 CI value of combination of 5-FU and eribulin

From: Synergistic antitumor effects of S-1 with eribulin in vitro and in vivo for triple-negative breast cancer cell lines

Combination ratio

Cell lines

5-FU (μM): eribulin (nM)

MDA-MB-231

MDA-MB-468

MX-1

BT-549

1 : 0.003

  

0.95

1.12

1 : 0.01

0.61

0.81

0.46

1.27

1 : 0.03

0.58

0.73

0.27

1.08

1 : 0.1

0.60

0.63

0.44

1.08

1 : 0.3

0.63

0.64

0.60

1.18

1 : 1

0.57

0.61

0.73

1.09

1 : 3

0.61

0.70

  
  1. The CI values were calculated in each combination ratio. The CI values of <1, 1, or >1 indicate synergism, additively, and antagonism, respectively.
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