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Table 1 IC50 value of 5-FU and eribulin

From: Synergistic antitumor effects of S-1 with eribulin in vitro and in vivo for triple-negative breast cancer cell lines

Cell lines

5-FU (μM)

Eribulin (nM)

TNBC

MDA-MB-231

13.0 ± 2.0

1.2 ± 0.3

MDA-MB-468

8.6 ± 2.5

0.7 ± 0.2

BT-549

5.3 ± 0.5

1.6 ± 0.2

MX-1

92.4 ± 3.7

4.3 ± 0.6

Non-TNBC

MCF-7

2.3 ± 0.4

0.4 ± 0.0

 

T47D

5.1 ± 0.4

2.6 ± 1.1

  1. Growth inhibitory effect of single agent 5-FU or eribulin in four TNBC cell lines and two non-TNBC cell lines. MTT assays were performed. The IC50 values of each agent were shown at 72 hours after exposure. Each value is the average ± SD of three independent experiments.
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