Table 2 Histologic features
Factor | NASH (N = 203) | Not NASH (N = 99) | p-value |
|---|---|---|---|
Steatosis | Â | Â | <0.001 |
  <5% | 0 (0.0) | 2 (2.0) |  |
  5-33% | 34 (16.7) | 68 (68.7) |  |
  34-65% | 85 (41.9) | 26 (26.3) |  |
  > = 66% | 84 (41.4) | 3 (3.0) |  |
Lobular inflammation | Â | Â | <0.001 |
  None | 5 (2.5) | 19 (19.2) |  |
  <2 under 20× | 147 (72.4) | 80 (80.8) |  |
  2–4 under 20× | 48 (23.6) | 0 (0.0) |  |
  >4 under 20× | 3 (1.5) | 0 (0.0) |  |
Portal inflammation | Â | Â | <0.001 |
  None | 48 (23.6) | 55 (55.6) |  |
  Mild | 134 (66.0) | 43 (43.4) |  |
  More than mild | 21 (10.3) | 1 (1.0) |  |
Ballooning* | Â | Â | <0.001 |
  None | 66 (32.8) | 94 (94.9) |  |
  Few | 55 (27.4) | 5 (5.1) |  |
  Many | 80 (39.8) | 0 (0.0) |  |
Fibrosis | Â | Â | <0.001 |
  0 | 33 (16.3) | 75 (75.8) |  |
  1 | 137 (67.5) | 18 (18.2) |  |
  2 | 15 (7.4) | 4 (4.0) |  |
  3 | 18 (8.9) | 2 (2.0) |  |
NAS* | 4.5 ± 1.4 | 2.2 ± 0.65 | <0.001 |