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Table 1 Eosinophilic granulomatosis with polyangiitis patients’ characteristics (case 1, 2)

From: Gastrointestinal perforation due to vasculitis at primary diagnosis of eosinophilic granulomatosis with polyangiitis (EGPA) despite a high dose glucocorticosteroids treatment

Characteristics   Patient 1 Patient 2
Time of diagnosis   4/2010 1/2009
Dosage of prednisolone a 80 mg 90 mg
Days of GC treatment b 7 10
Manifestations of EGPA    
  Heart failure (NYHA stage) II II
Myocarditis c Present Present
Neuropathy Mononeuritis multiplex L1 Polyneuropathy
Lung Bronchial asthma Asthma bronchiale
  Eosophile infiltration  
Kidney Mild proteinuria (0.5 g/24 h) Glomerular hematuria
Eosinophilic granulocytes d 5500/μl 4900/μl
IgE value   Elevated Elevated
pANCA value (Positive) e 12.8 U/mlf 14.1 U/mlf
  1. aintraveneous application once a day; bGC = glucocorticosteroides, till perforation followed by abdominal surgery; EGPA = eosinophilic granulomatosis with polyangiitis; chistological proved by myocardial biopsy; dcounted in periphereal blood; epANCA = perinuclear pattern of antineutrophilic cytoplasmatic autoantibodies, tested by immunofluorescence test and by ELISA for myeloperoxidase autoantibodies (anti-MPO) fin U/ml; NYHA = New York Heart Association classification of heart failure.