Figure 6

Selective cytotoxic effect of NEAPP-AM on TOV21G cells compared with OHFC and HPMC. Cell viability of TOV21G, OHFC, and HPMC after being treated with NEAPP-AM-8 was measured by the cell viability assay. Cells were seeded in collagen-coated 96-well plates and incubated for 24 hrs, the culture medium was replaced with NEAPP-AM, and the cells were incubated for another 24 hrs. The cell proliferation rate was evaluated relative to the control with the cell viability assay. *P < 0.05, **P < 0.01 versus TOV21G treated with NEAPP-AM-8.