Dosage | Age | Baseline | 21 days after injection | 42 days after injection | ||
---|---|---|---|---|---|---|
GMT (95% CI) | GMT (95% CI) | GMI (95% CI) | GMT (95% CI) | GMI (95% CI) | ||
15 μg | 6-12 m | 7.58 | 16.63 | 2.19 | 145.88 | 19.25 |
(4.34 ~ 13.24)b | (8.11 ~ 34.07)b | (1.30 ~ 3.69)b | (80.39 ~ 264.73)a | (12.32 ~ 30.08)a | ||
13-24 m | 13.75 | 63.90 | 4.65 | 255.56 | 18.59 | |
(9.03 ~ 20.94) | (37.46 ~ 108.97)a | (3.22 ~ 6.70)a | (170.61 ~ 382.91)a | (11.59 ~ 29.81)a | ||
25-35 m | 10.37 | 65.45 | 6.31 | 226.26 | 21.82 | |
(6.50 ~ 16.55) | (40.06 ~ 106.95)a | (4.14 ~ 9.62)a | (151.81 ~ 337.21)a | (13.80 ~ 34.48)a | ||
Total | 11.05 | 51.57 | 4.67 | 221.11 | 20.00 | |
(8.42 ~ 14.51) | (37.07 ~ 71.76)a | (3.63 ~ 6.00)a | (172.15 ~ 283.99)a | (15.19 ~ 26.34)a | ||
7.5 μg | 6-12 m | 22.32 | 66.67 | 2.99 | 276.57 | 12.39 |
(9.97 ~ 49.91) | (28.58 ~ 155.49)a | (1.85 ~ 4.81)a | (166.88 ~ 458.35)a | (7.16 ~ 21.44)a | ||
13-24 m | 7.63 | 25.34 | 3.32 | 116.04 | 15.21 | |
(5.67 ~ 10.27) | (15.15 ~ 42.39)a | (2.24 ~ 4.93)a | (75.11 ~ 179.31)a | (10.57 ~ 21.89)a | ||
25-35 m | 10.70 | 43.53 | 4.07 | 180.09 | 16.83 | |
(6.87 ~ 16.65) | (28.89 ~ 65.58)a | (2.85 ~ 5.80)a | (124.11 ~ 261.33)a | (11.20 ~ 25.30)a | ||
Total | 10.71 | 37.86 | 3.54 | 163.34 | 15.25 | |
(8.22 ~ 13.95) | (27.83 ~ 51.50)a | (2.82 ~ 4.44)a | (127.06 ~ 209.94)a | (12.03 ~ 19.33)a | ||
SI | 6-12 m | 9.33 | 8.71 | 0.93 | 14.14 | 1.52 |
(3.62 ~ 24.08) | (3.77 ~ 20.09) | (0.80 ~ 1.09) | (4.70 ~ 42.60) | (0.69 ~ 3.31) | ||
13-24 m | 7.87 | 8.52 | 1.08 | 12.05 | 1.53 | |
(4.68 ~ 13.22) | (5.51 ~ 13.18) | (0.83 ~ 1.41) | (7.67 ~ 18.94) | (1.10 ~ 2.13) | ||
25-35 m | 8.71 | 8.01 | 0.92 | 14.74 | 1.69 | |
(5.30 ~ 14.29) | (5.19 ~ 12.37) | (0.81 ~ 1.04) | (8.57 ~ 25.35) | (1.19 ~ 2.41) | ||
Total | 8.43 | 8.34 | 0.99 | 13.44 | 1.59 | |
(6.14 ~ 11.58) | (6.35 ~ 10.95) | (0.87 ~ 1.12) | (9.74 ~ 18.54) | (1.28 ~ 1.99) |