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Figure 1

From: Effects of combined netupitant and palonosetron (NEPA), a cancer supportive care antiemetic, on the ECG of healthy subjects: an ICH E14 thorough QT trial

Figure 1

Placebo- and baseline-corrected change in QTcI. (a) Placebo- and baseline-corrected change in QTcI for each time point in each treatment group. (b) Pharmacokinetic/pharmacodynamics relationship: placebo- and baseline-corrected change in QTcI versus netupitant plasma concentrations and (c) versus palonosetron plasma concentrations.

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