Table 5 Scoring scheme regulated expression FA/BRCA genes
| Cell cycle model | RB1/E2F disturbed cancers | |||||
|---|---|---|---|---|---|---|
| Part | Gene symbol | T98G | EVA-F | Retinoblastoma | Basal breast tumors | Total |
| Core complex | FANCA | 1 | 1 | 1 | 1 | 4 |
| FANCB | 1 | 1 | 0 | 1 | 3 | |
| FANCC | 0 | 1 | 0 | 0 | 1 | |
| FANCE | 1 | 0 | 0 | 0 | 1 | |
| FANCF | 0 | 0 | 0 | 0 | 0 | |
| FANCG | 1 | 1 | 1 | 0 | 3 | |
| FANCL | 0 | 1 | 1 | 0 | 2 | |
| FANCM | 1 | 1 | 0 | 0 | 2 | |
| Central players | FANCD2 | 1 | 1 | 0 | 0 | 2 |
| FANCI | 1 | 1 | 1 | 0 | 3 | |
| Downstream branch | FANCD1/BRCA2 | 1 | 1 | 1 | 0 | 3 |
| FANCN/PALB2 | 1 | 1 | 1 | 0 | 3 | |
| BRCA1 | 1 | 1 | 1 | 0 | 3 | |
| FANCJ/BRIP1 | 1 | 1 | 1 | 0 | 3 | |