Figure 2

Decision tree(s) to select coregulated genes. (a) Decision tree for selecting FA/BRCA genes that are regulated through the cell cycle. (b) Decision tree to select FA/BRCA genes in RB1/E2F disturbed cells. Two cell models: retinoblastoma and breast cancer cells are screened. In both models a selection is made for “Regulated” or “Non-Regulated”. In case of “Regulated” a selection is made on the possible influence of copy number alterations (CNA). Abbreviations: P = P-value; MFC = mean fold change; FC = fold change; LC = linear correlation; CNA = copy number alteration.