Figure 3From: Suggestion of suitable animal models for in vivo studies of protein tyrosine phosphatase 1b (PTP1B) inhibitors using computational approachesVariations in important binding sites of some sequences – (a) R24 second aryl binding site and pTyr recognition site; (b) R254 & G259 second aryl binding site and Q-loop motif. Conserved residues in these positions are shown in red. The yellow square indicates 6 species that have vigorous variations in these regions.Back to article page