From: Hypocapnia delays subsequent bupivacaine cardiotoxicity in rats under sevoflurane anesthesia
HR-25 | HR-50 | MAP-25 | MAP-50 | ||
---|---|---|---|---|---|
Control group (n = 9) | Time(s) | 298 (171) | 818 (357) | 330 (199) | 1111 (431) |
Total doses of bupivacaine infused (mg · kg−1) | 9.9 (5.7) | 27.3 (11.9) | 11.0 (6.6) | 37.1 (14.4) | |
Hypocapnia Group (n = 9) | Time(s) | 305 (137) | 1818 (347)* | 1739 (779)* | 2319 (440)* |
Total doses of bupivacaine infused (mg · kg−1) | 10.1 (4.6) | 60.6 (11.5)* | 58.0 (26.0)* | 77.3 (14.7)* |