|
Categorical factor
|
Dose reduction due to other reasons (N=28)
|
CIPN dose reduction (N=21)
|
p-value1
|
|---|
| |
N(row%)
|
N(row%)
| |
|---|
|
Her2
| | | |
|
Negative
|
22 (58)
|
16 (42)
|
1.00
|
|
Positive
|
6 (55)
|
5 (45)
| |
|
Agent
| | | |
|
Paclitaxel only
|
4 (22)
|
14 (78)
|
0.001
2
|
|
Docetaxel only
|
20 (80)
|
5 (20)
| |
|
Multiple agents3
|
4 (67)
|
2 (33)
|
0.68
|
|
Alcohol
| | | |
|
No
|
27 (57)
|
20 (42)
|
1.00
|
|
Yes
|
1 (50)
|
1 (50)
| |
|
Diabetes
| | | |
|
No
|
22 (61)
|
14 (39)
|
0.51
|
|
Yes
|
6 (46)
|
7 (54)
| |
|
Race
| | | |
|
Black
|
14 (47)
|
16 (53)
|
<0.001
4
|
|
White
|
14 (78)
|
4 (22)
| |
|
Other
|
0
|
1 (100)
| |
|
Continuous Factor
|
Mean (range)
|
Mean (range)
| |
|
Age (years)
|
55 (42–75)
|
55 (35-67)
|
0.84
|
- 1p-values calculated with the use of two-sided Fisher’s and Fisher-Freeman-Halton’s tests for categorical variables and the t-test for continuous variables.
- 2Patients treated with paclitaxel (or nab- paclitaxel) only vs. those treated with docetaxel only.
- 3Patients treated with multiple agents, compared to those treated with either paclitaxel only or docetaxel only.
- 4Black compared to white only.
