Table 2 Interaction parameters of HU-HSA system at different temperatures
From: Elucidation of binding mechanism of hydroxyurea on serum albumins by different spectroscopic studies
Temp. (K) | Ksv × 10-4M-1 | Kq × 10-12M-1S-1 | Binding constant K × 10-4M-1 | No. of binding sites n | ΔH0(k J mol-1) | ΔS0(J K-1mol-1) | ΔG0(k J mol-1) |
|---|---|---|---|---|---|---|---|
288 | 0.5042 | 0.5042 | 1.1601 | 1.09 | |||
298 | 0.8949 | 0.8949 | 4.3863 | 1.17 | 102.94 ± 3.0 | 434.95 ± 12.0 | -26.67 ± 2.0 |
308 | 1.1019 | 1.1019 | 18.958 | 1.28 |