IL17RC overexpression increases complexes of C3/β-Catenin, C3/GSK3β or C3/VEGF. In A to C, confocal microscopy procedures were applied to EV-transfected ARPE or IL17RC-transfected ARPE treated without or with sFRP2. Images and treatments are labeled in the figures, big C3 complexes are indicated by arrows, and damaged cells are red-framed. DAPI is the intensity control and phase shows cell-surface. Data represent three separate experiments.