Willingness to pay to avoid metastatic breast cancer treatment side effects: results from a conjoint analysis

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Table 3 Average value to patient of a reduction in side effects

Attribute	Levels	Value to patient	Average value to patient	Importance
Hair loss	None/not noticeable	0.5374	0.5374	6
Hair loss	Obvious	-0.5374	0.5374	6
Fatigue	None/full activity	0.6941	0.5628	5
	I often need a nap to reset myself	0.1501
	Major impact on my activity level	-0.8841
Nausea	None/easy to ignore	0.7060	0.7709	3
	Manageable with OTC medication (eg, Advil, Tylenol)	0.0854
	Need prescription-strength medication	-0.4654
Diarrhea	2 stools or less per day	0.9371	0.8809	2
	3+ loose stools per day	0.3842
	Unable to leave the house due to frequency and urgency of diarrhea	-1.3213
Risk of infection	None/modest	1.090	1.090	1
Risk of infection	Hospitalized due to infection	-1.090	1.090	1
Tingling in hands and feet	None/easy to ignore	0.6693	0.6624	4
	Bothersome, but manageable	0.2643
	Interferes with daily activities (eg, getting dressed)	-0.9336

The average value to patients is the part-worth utility calculated using effects coding. The relative importance of each attribute was determined based on the range of each attribute’s utility values.