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Table 1 Clinical presentation

From: Bone marrow fibrosis as a feature of systemic lupus erythematosus: a case report and literature review

Nref

Age (yrs)

M/F

PD SLE

SLE symptoms and signs

Associed symptoms and signs

LNE

HMG

SMG

1 (Sarkar et al.2009)

45

M

-

Pleural effusion

Fever, melena, epistaxis

-

-

-

2 (Sacre et al.2009)

44

F

+

Diffuse alopecia, arthritis

   

-

3 (Pillai et al.2009)

40

F

-

Proteinuria, pleural and pericardial effusion, ascites

Fever

-

+

-

4 (Aziz et al.2004)

22

F

-

Membranous nephropathy

Fever, epistaxis

+

+

+

5 (Kiss et al.2000)

18

F

+

Alopecia, facial erythema, arthritis

Fever, weight loss, myositis

 

-

-

6 (Durupt et al.2000)

29

F

+

Polyarthritis, mesangial glomerulonephritis

Fever, hematuria

-

-

-

7 (Vora et al.1998)

22

F

+

Membranous nephropathy, seizures

Severe recurrent posterior scleritis

  

+

8 (Aharon et al.1997; Amital et al.2003)

54

F

-

Arthralgias, pleural effusion

Fever, weight loss, abdominal pain

+

+

+

9 (Agarwal et al.1995)

12

F

+

NS

Fever, petechias

-

-

-

10 (Ramakrishna et al.1995)

18

F

-

Alopecia, arthralgias, Evans’ syndrome

Fever, weight loss, menorrhagia, headaches

-

-

-

11 (Paquette et al.1994)

68

M

-

Pleural effusion, oral ulcers

   

-

12 (Paquette et al.1994)

27

F

-

NS

Epistaxis, hematuria, gingival bleeding, petechias

+

 

+

13 (Paquette et al.1994)

23

F

+

Photosensitivity, alopecia, malar rash, pharyngeal ulcerations, arthritis, oral ulcers

Gingival bleeding, retinal lesion

 

+

+

14 (Paquette et al.1994)

56

F

+

Alopecia, arthritis

Cutaneous vasculitis

  

-

15 (Paquette et al.1994)

18

F

-

NS

Fever, menorrhagia, epistaxis, gingival bleeding, petechias

+

+

+

16 (Paquette et al.1994)

70

F

-

Arthritis, pleural effusion

Fever, weight loss, hematemesis

  

-

17 (Paquette et al.1994)

62

F

-

Psychosis

Fever, weight loss, panniculitis

 

+

+

18 (Paquette et al.1994)

69

F

+

Arthritis, immune thrombocytopenia

Petechias

 

+

S

19 (Hirose et al.1993)

54

F

+

Oral ulcers, polyarthralgias

Fever, weight loss

   

20 (Borba et al.1993)

39

F

+

Malar rash, photosentivity, alopecia, Raynaud’s, arthritis, pericarditis, pleural effusion

Fever

   

21 (Foley-Nolan et al.1992)

20

F

-

Arthralgias

   

-

22 (Inoue et al.1992)

24

F

-

Proteinuria

Fever, purpura

-

-

-

23 (Matsouka et al.1989)

60

F

-

Proteinuria, immune thrombocytopenia

Fever, weight loss, petechias and ecchymoses

 

+

S

24 (el Mouzan et al.1988)

13

F

-

Arthritis

Fever, anorexia, petechias and ecchymoses

+

+

+

25 (Kaelin and Spivak1986)

27

F

+

Hyperpigmented skin rash, polyarthralgias

Ecchymoses, epistaxis, melena, gingival bleeding, purpura

-

-

-

26 (Nanji and Jetha1984)

28

M

+

Erythematous macular lesions, arthritis, deterioration in renal function, pleural and pericardial effusion, ascites

Fever

 

+

+

27 (Daly and Scott1983)

16

F

-

Alopecia, arthritis

Weight loss, subcutaneous nodules in hands, retinal exudates, epistaxis, gingival bleeding, purpura and ecchymoses

+

+

+

Present

29

F

+

Photosensitivity, polyarthralgias and Raynaud’s phenomenon

Fever, edema

-

-

+

  1. PD: previous diagnosis of SLE, LNE: lymph node enlargement, HMG: hepatomegaly, SMG: splenomegaly, S: splenectomy, NS: not specified.