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Table 1 Clinical presentation

From: Bone marrow fibrosis as a feature of systemic lupus erythematosus: a case report and literature review

Nref Age (yrs) M/F PD SLE SLE symptoms and signs Associed symptoms and signs LNE HMG SMG
1 (Sarkar et al.2009) 45 M - Pleural effusion Fever, melena, epistaxis - - -
2 (Sacre et al.2009) 44 F + Diffuse alopecia, arthritis     -
3 (Pillai et al.2009) 40 F - Proteinuria, pleural and pericardial effusion, ascites Fever - + -
4 (Aziz et al.2004) 22 F - Membranous nephropathy Fever, epistaxis + + +
5 (Kiss et al.2000) 18 F + Alopecia, facial erythema, arthritis Fever, weight loss, myositis   - -
6 (Durupt et al.2000) 29 F + Polyarthritis, mesangial glomerulonephritis Fever, hematuria - - -
7 (Vora et al.1998) 22 F + Membranous nephropathy, seizures Severe recurrent posterior scleritis    +
8 (Aharon et al.1997; Amital et al.2003) 54 F - Arthralgias, pleural effusion Fever, weight loss, abdominal pain + + +
9 (Agarwal et al.1995) 12 F + NS Fever, petechias - - -
10 (Ramakrishna et al.1995) 18 F - Alopecia, arthralgias, Evans’ syndrome Fever, weight loss, menorrhagia, headaches - - -
11 (Paquette et al.1994) 68 M - Pleural effusion, oral ulcers     -
12 (Paquette et al.1994) 27 F - NS Epistaxis, hematuria, gingival bleeding, petechias +   +
13 (Paquette et al.1994) 23 F + Photosensitivity, alopecia, malar rash, pharyngeal ulcerations, arthritis, oral ulcers Gingival bleeding, retinal lesion   + +
14 (Paquette et al.1994) 56 F + Alopecia, arthritis Cutaneous vasculitis    -
15 (Paquette et al.1994) 18 F - NS Fever, menorrhagia, epistaxis, gingival bleeding, petechias + + +
16 (Paquette et al.1994) 70 F - Arthritis, pleural effusion Fever, weight loss, hematemesis    -
17 (Paquette et al.1994) 62 F - Psychosis Fever, weight loss, panniculitis   + +
18 (Paquette et al.1994) 69 F + Arthritis, immune thrombocytopenia Petechias   + S
19 (Hirose et al.1993) 54 F + Oral ulcers, polyarthralgias Fever, weight loss    
20 (Borba et al.1993) 39 F + Malar rash, photosentivity, alopecia, Raynaud’s, arthritis, pericarditis, pleural effusion Fever    
21 (Foley-Nolan et al.1992) 20 F - Arthralgias     -
22 (Inoue et al.1992) 24 F - Proteinuria Fever, purpura - - -
23 (Matsouka et al.1989) 60 F - Proteinuria, immune thrombocytopenia Fever, weight loss, petechias and ecchymoses   + S
24 (el Mouzan et al.1988) 13 F - Arthritis Fever, anorexia, petechias and ecchymoses + + +
25 (Kaelin and Spivak1986) 27 F + Hyperpigmented skin rash, polyarthralgias Ecchymoses, epistaxis, melena, gingival bleeding, purpura - - -
26 (Nanji and Jetha1984) 28 M + Erythematous macular lesions, arthritis, deterioration in renal function, pleural and pericardial effusion, ascites Fever   + +
27 (Daly and Scott1983) 16 F - Alopecia, arthritis Weight loss, subcutaneous nodules in hands, retinal exudates, epistaxis, gingival bleeding, purpura and ecchymoses + + +
Present 29 F + Photosensitivity, polyarthralgias and Raynaud’s phenomenon Fever, edema - - +
  1. PD: previous diagnosis of SLE, LNE: lymph node enlargement, HMG: hepatomegaly, SMG: splenomegaly, S: splenectomy, NS: not specified.
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