Effects of milk-fat globule membrane (MFGM) on production of MuSK and Dok-7 proteins. Levels of production of the proteins MuSK (A), and Dok-7 (B) were measured by western blot analysis. The quadriceps muscle was removed from each mouse in the non-fasting, resting condition. Tissue lysates were then prepared and subjected to western blot analysis. Values are means ± S.E. of 7 or 8 mice. †P < 0.05, significant difference between ICR group and control SAMP1 group by unpaired t-test. **P < 0.01, significant difference vs. Control SAMP1 group by Fisher’s PLSD posthoc test. Values are expressed as ratios, using the value of the control SAMP1 group as 1.0. MFGMEx, MFGM plus habitual exercise.