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Figure 3

From: Habitual exercise plus dietary supplementation with milk fat globule membrane improves muscle function deficits via neuromuscular development in senescence-accelerated mice

Figure 3

Effects of milk-fat globule membrane (MFGM) on expression of genes associated with nervous system development and function-related molecules. mRNA expression levels of MuSK (A), Dok-7 (B), NCAM (C), MyoD (D), and myogenin (E) were measured using quantitative real-time PCR. Expression of each gene was normalized against that of the housekeeping gene encoding ribosomal protein, large, P0 (RPLP0/36B4). Values are means ± S.E. of 7 or 8 mice. ††P < 0.01 and †P < 0.05, significant difference between ICR group and control SAMP1 group by unpaired t-test. *P < 0.05, significant difference vs. control SAMP1 group by Fisher’s PLSD posthoc test. Values are expressed as ratios, using the value of the control SAMP1 group as 1.0. MuSK, muscle skeletal receptor-tyrosine kinase; Dok-7, docking protein-7; NCAM, neural cell adhesion molecule; MyoD, myogenic differentiation; MFGMEx, MFGM plus habitual exercise.

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