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Table 3 Summary of the event distribution probabilities for the simulated scenarios

From: Interim analysis for binary outcome trials with a long fixed follow-up time and repeated outcome assessments at pre-specified times

Scenario Event distribution probabilities by visit time
t 1 , t 2 , t 3 , t 4
Standard group Experimental group
1 0.25, 0.25, 0.25. 0.25 same as standard
2 0.35, 0.30, 0.20, 0.15 same as standard
3 0.15, 0.20, 0.30, 0.35 same as standard
4 0.15, 0.20, 0.30, 0.35 0.35, 0.30, 0.20, 0.15
5 0.35, 0.30, 0.20, 0.15 0.15, 0.20, 0.30, 0.35