Table 2 Summary of six trials considered for simulation with β = 0.10 and a one-sided α = 0.025
Standard group event proportion (π0) | Experimental group event proportion (π1) | Absolute risk reduction (π0-π1) | N |
|---|---|---|---|
0.30 | 0.25 | 0.05 | 3342 |
0.30 | 0.20 | 0.10 | 796 |
0.30 | 0.10 | 0.20 | 160 |
0.50 | 0.45 | 0.05 | 4182 |
0.50 | 0.40 | 0.10 | 1030 |
0.50 | 0.30 | 0.20 | 242 |